Sigma Metric Analysis
In 2016, Clinical Biochemistry published a study evaluating the Sigma-metrics of the Beckman Coulter Olympus AU 680 using biological variation goals.
In 2017, Clinical Chemistry published a study evaluating the trueness of 24 Serum Albumin methods.
Recently, with the help of some Chinese laboratorians, we translated the studies of Sigma-metrics of several chemistry instruments.
Back in 2011, we took a look at the Olympus AU 2700 plus. In 2016, it's time to take a look at the more recent models, like the Olympus AU 5800.
Bias exists! And in a recent Clinical Chemistry study, the authors found unacceptably large biases in 4 out of 5 common immunoassays: cobalamin, folate, ferritin, TSH, and Free T4. Does a Sigma-metric analysis agree with this judgment?